Steve Eppinger was invited to deliver the autumn 2019 Technical University of Denmark Ørsted Lecture. The aim of the lecture series is “to stimulate new thoughts and new scientific approaches by presenting topics that will change our future,” with “the most advanced and frontier breaking research.” This biannual event commemorates the university’s founder, Hans Christian Ørsted, who discovered electromagnetism. Eppinger joins a distinguished list of invited lecturers who are leading scientists from the fields of science and engineering, including several Nobel laureates.